Looking for Alternative Cancer Treatment?  We Can Help

Have you or a loved one been diagnosed with cancer? Are you feeling that your treatment options are limited or are you looking for additional ones? Every year thousands of cancer patients from all around the world travel to Sunridge Medical in search for new treatment options to help them with their cancer. We know it can be overwhelming trying to decide which treatment direction to take. Our goal at Sunridge Medical is to offer patients suffering with cancer additional treatment options and education to help.

Whatever your circumstance, Sunridge is here to help you. We offer comprehensive personalized treatment plans that are tailor-made specific to your individual needs utilizing an optimal combination of the latest advanced research-based treatment options from around the world. It is our opinion that a one-size fits all approach to cancer treatment is riddled in failure. Treatment needs to be personalized. If your current treatment plan is holding you back or you need more options, give us a call at (800) 923-7878.

Our Alternative Cancer Treatment Strategy

senior_man_wifeAt Sunridge Medical we offer a comprehensive immunobiological treatment program that aims to not only attack the cancer, but also restore the body’s natural defense and regulatory mechanisms including the immune system and detoxification pathways. We offer support through successfully proven individualized alternative cancer treatments which are based on a blend of traditional medication and advanced, research-based natural medicines. Through this integrated, holistic and comprehensive approach, we are able to identify and treat the underlying causes of the cancer as well as increase the health of the body and improve quality of life. This approach sets us apart from traditional medical clinics and, most importantly, allows for ultimate patient success.

Research has shown that cancer cells develop in every human being. However, just because a cancer cell is produced in the body does not mean that this will lead to the formation of a tumor or subsequent metastasis. Because of the body’s natural defense system which consists of an immune surveillance system, a repair mechanism and other regulatory mechanisms that detect newly produced cancer cells, cancer cells are identified and destroyed before they become tumors. As long as this natural defense system is functioning properly, the body is able to protect itself from cancer.

In all cancer patients, the body’s natural defense system is not functioning optimally which means that when a cancer cell is present, it is not destroyed and can continue to grow. Knowing this, once diagnosed with cancer, it is very important to make sure that restoration of the body’s natural defense system is included in your alternative cancer treatments.

Our Strategy

  • Attack the Cancer to stop tumor(s) growth is the first step. This allows us to focus on regression or shrinking of the tumor(s) and onward, until complete dissipation.
  • Restoration of the body’s natural cancer-fighting mechanisms which include normalizing the regulatory mechanisms responsible for cellular metabolism, defense, repair and detoxification.
  • Attain and maintain remission status

Get Started Now!

We Want To Hear From You! Take the first step towards feeling better and use the form below to contact our Patient Care Representatives. (** All Fields Required **)

Hear From Some of Our Patients 

3 Patients Brain Cancer / Lung Cancer / Breast Cancer

Jill’s tumor left doctor’s unsure of how surgery may affect her, but decisions had to be made fast. After a poor prognosis from conventional doctors, Jill chose alternative treatment at Sunridge to builder her immune system to fight her cancer dangerous tumor she had in her brain.

Jill, Alberta Canada

Alternative Breast Cancer and Type 1 Diabetes Treatment

Louie talks about how his wife is in remission from stage 4 breast cancer with the help of Sunridge Medical. After his wife’s treatment, Sunridge also helped cure him of Type 1 Adult Onset Diabetes! After taking insulin for the last 4 years, he now takes none.

Louie, Indiana

The Most Common Cancers We Treat

We offer comprehensive, advanced research-based treatment options for patients with many different types of cancer. Below are some of the most common cancers that we see. Click on the links below for more information on cancer treatment options. Our therapies work in conjunction with traditional therapies or by themselves. If you have been diagnosed with cancer at any stage, talk to our patient care representative to see how Sunridge Medical can help by providing superior alternative cancer treatment. Hear what our patients say about their experiences at Sunridge.

We treat most cancers at any stage of diagnosis. Below are some of the most common, but not necessarily a comprehensive list. For questions about a certain type of cancer or treatment please contact our patient care representative at 1-800-923-7878.

Frequently Asked Cancer Questions

At Sunridge Medical we offer a full immuno-biological treatment program that aims to not only attack the cancer, but also restore the body’s natural defense and regulatory mechanisms including the immune system and detoxification pathways. Through this holistic approach, we are able to identify and treat the underlying causes of the cancer as well as increase the body’s health, and enhance the quality of life for our patients. Below are some questions that people just like you have asked when considering alternative cancer treatment for themselves or a loved one.

Depending on the type and stage of your cancer, your treatment frequency can vary from 3 to 6 times per week. For patients who are actively undergoing chemotherapy or radiation treatments, this may vary further depending on how often those treatments are received.
Side effects from treatments received at Sunridge are very infrequent. Usually patients feel an improvement in their symptoms rather than additional symptoms. On occasion, a patient may experience mild nausea if the infusion is dripping too quickly. This side effect is resolved by slowing down the drip speed.
This depends and is determined on a patient-by-patient basis. Many of our patients receive our alternative cancer treatment in addition to receiving chemotherapy or radiation. Unfortunately, stabilization or remission of an advanced disease such as stage III or IV cancer has shown to be difficult when receiving chemotherapy or radiation alone.
• All patients who have been diagnosed with cancer.

• Patients who have tried conventional treatments, but are unable to tolerate the side effects.

• Patients who have failed convention cancer treatment (surgery, radiation and chemotherapy)

• Patient who have Stage III or Stage IV cancers

If you have stage IV cancer where the tumor has spread to other areas of the body (metastasis), it is important that you realize that treatment with chemotherapy alone will rarely cure your disease.

Absolutely. Just give our Patient Care Representatives a call at (800) 923-7878 and they can make arrangements for you. We also have a growing video library of Patient Experiences on our Media page that are very informational.
Give us a call. We have relationships with many hotels and resorts in the area that offer special pricing to our patients. Most of our patients receiving our supportive alternative cancer treatment fly to see us.

If you have any additional questions or would like more information about our services and holistic treatment options please call us at (800) 923-7878. Our patient care representatives are waiting to help you.

Individualized Cancer Treatment with Advanced Natural Medicine

We offer comprehensive, advanced research-based treatment options for patients with many different types of cancer. Below are some of the most common cancers that we see. Click on the links below for more information on cancer treatment options. Our therapies work in conjunction with traditional therapies or by themselves. If you have been diagnosed with cancer at any stage, talk to our patient care representative to see how Sunridge Medical can help by providing superior alternative cancer treatment. Hear what our patients say about their experiences at Sunridge.

We treat most cancers at any stage of diagnosis. Below are some of the most common, but not necessarily a comprehensive list. For questions about a certain type of cancer or treatment please contact our patient care representative at 1-800-923-7878.

Because each cancer patient has unique circumstances surrounding their illness, even those with the same type of cancer, all of our recommended treatments are customized to each patient. Click on the links below to review some of our cancer therapies.

Many of our treatments are aimed at rebuilding a compromised immune system damaged from the toxicity of chemotherapy and radiation, while also having specific cancer-fighting properties. Our therapies ease the nausea and illness associated with chemo, providing patients a shorter downtime. In stage 4 cancers this is most beneficial for patients who need an aggressive fight and cannot afford the downtime associated with chemotherapy.

Having a strong immune system is critical to the fight against existing cancer which is why some choose alternative cancer therapies as a first line of defense. Similarly, maintaining a strong immune system helps prevent the recurrence of cancer and other illnesses. Pairing any cancer therapy, especially chemotherapy, with an immunotherapy treatment is critical to the eradication and prevention of cancer recurrance. Chemotherapy is a toxic chemical and a leading cause of cancer recurrence.

Advanced Natural Cancer Therapies

Need Post Chemotherapy Recovery Plan?

If you have completed chemotherapy and are suffering from side affects and a decreased quality of life, we can help. You know that during your fight, both the disease and its treatment have left marks on your body and mind. Your healthy cells have been attacked and your immune system has been compromised. While everybody reacts differently to chemotherapy drugs, everyone endures lasting effects of the regimen.

At Sunridge Medical, we are here to help you recover physically and emotionally. Our doctors take the time to sit down with you and assess your current health condition and design a specific treatment plan tailored to your needs. While traditional treatment methods attack the cancer cells, we address the underlying causes of your cancer. Our goal is to help rebuild your immune system and also detoxify your body of any harmful elements. You have been through the worst of it and now you deserve to have your life back. Even if you are still accepting chemotherapy and/or radiation, at Sunridge Medical, our program can help minimize the side effects and help you get back on track.

Breast Cancer Treatment

On the day of receiving the good news that her PET scan came back clean, a patient talks about Dr. Franco and the success of the alternative treatments she received at Sunridge Medical Center in Scottsdale, Arizona.  Jen could not do chemotherapy.  She tried but had to quite since it left her debilitated in bed for two weeks after each session

Jen, Michigan

Advanced Diagnostic Cancer Testing and Tools

Learn about our advanced diagnostic tools and testing. At Sunridge, we pride ourselves on delivering the most accurate results by using only the most trusted tools and testing. We understand how critical accuracy is when it comes to your health. We provide advanced diagnostic tools and testing that can help you get the most out of conventional therapies or alternative therapies. When it comes to the health of our patients we strive for accurate, timely and comprehensive reports. After a thorough consultation, together, we create the right testing and treatment. For additional questions regarding the type of diagnostics and testing we use at Sunridge, contact our patient care representative at 1-800-923-7878.

Learn About Our Pre-Chemo Testing

Have you been prescribed chemotherapy by your doctor?. Find out what the most effective chemotherapy drugs are for your specific cancer thru chemosensitivity testing. Trial and error can be the difference between cancer treatment success and failure.

The main reason for the high mortality caused by cancer is too late detection of the disease. Higher cure rates are achieved if the disease was detected in the beginnings of an early stage. To increase the chance of surviving cancer, it is important to detect the very first signs of a neoplasia. Advanced testing allows us to screen for cancer by using body fluids such as blood, urine and sputum.

Usually, cancer screening and foresight is done by imaging techniques. Standard imaging techniques may have the drawbacks of low sensitivity or to be uncomfortable (e.g. colonscopy). As a consequence, foresight by imaging techniques may be consulted too infrequently or the disease is perhaps detected in a progressed stage. To reduce overall cancer morality, diagnostic methods are required which are sensitive and well tolerated. Acceptance for foresight examinations may be raised if the test is non-invasive, i.e. it can be performed with body fluids like blood, urine, or stool which are easily accessible.

Molecular techniques allow the detection of genetic alterations typically observed in tumors. Cancer is a multi-factorial genetic disease, i.e., multiple genetic alterations have to occur in combination so that a malignant cancer cell can emerge. The very first genetic alterations during the evolution of a cancer cell can be detected in pre-cancerous lesions as well as in the tumors which arose thereof. The presence of such early signs in a patient must not inevitably lead to cancer, but can be considered as a risk factor. As a consequence of the detection of risk factors, changes in nutritional and environmental behavior may be applicable as well as enhanced vigilance to monitor for further progression. We provide several assays for the detection of cancer risk factors from different body fluids:

From blood

This diagnostic test is done on an individual because of clinical suspicion of disease. Because tumor cells can be disseminated to the blood stream early, a cancer screening test can be done with peripheral blood. Improvements in technology made it possible to detect even a few tumor cells. Moreover, detection of disseminated cells can be used to monitor the efficiency of treatment. If the therapy is effective, minimal residual cancer cells should disappear from the bloodstream. A limitation of this assay is that it cannot be specified from which body site these tumor cells are scattered into the blood stream. Furthermore, the neoplasia must also have already progressed and gained access to the circulation. To overcome this limitations, we established detection assays using organ-confined specimens (urine, sputum) allowing a closer localisation of the source of the neoplastic cells.

From urine

Pre-malignant and malignant cells of prostate cancer or bladder cancer are shed in the urine. We have established molecular tests for the detection of genetic alterations typically seen in such tumors. Urinary detection of these alterations can be indicative for these cancers or pre-malignancies.

From sputum

Smokers are at higher risk for developing lung cancer. However, only about 20 % of smokers are affected. It is therefore important to identify those individuals which already progressed to a higher risk state. Pre-malignant and malignant cells of lung-cancer can be detected in sputum. We have established molecular tests for the detection of genetic alterations typically seen in such tumors. Detection of these alterations can be indicative for such cancers or pre-malignancies.

Read More
Doctors prescribe chemotherapy drugs based on their experience and the data documented in clinical trials. While these methods are sensible, there are too many other variables between individuals that can produce a-typical results more often than one would think. Chemosensitivity testing can help lower instances of cancer recurrence by guiding patients in choosing the most effective drug the first time around. Because it targets residual cells that are actually different in their genetic makeup than cells from the primary tumor, chemosensitivity testing is a more targeted approach to cancer treatment. By eliminating drugs that show resistance, chemosensitivity testing can help you make the best choices for your treatment. As with anything, absolute certainty is impossible, but the use of diagnostic testing and tools to complement chemotherapy can greatly minimize instances of cancer recurrence.

You’re more than halfway through the worst part of cancer – chemotherapy, only to find out the cancer cells were resistant to the drugs. With only 3 treatments remaining you begin to wonder if it will be enough …

Testing For Chemotherapy Drug Effectiveness – Before Treatment

Sunridge Medical believes all patients should make the most informed decisions about what’s best for them in terms of their health. In cases of serious illness like cancer these decisions can have a significant impact on the end result of their treatments.

Choosing chemotherapy as a first line of defense against cancer or as an adjuvant therapy,[1] may be the best treatment option for you, but can also have varying degrees of effectiveness for different people. For example, certain types of cancers have shown to respond better or worse to certain types of chemotherapy drugs. Doctors prescribe chemotherapy drugs based on their experience and the data documented in clinical trials. While these methods are sensible, there are too many other variables between individuals that can produce a-typical results more often than one would think.

Gene Profiling and Drug Resistance “The cells responsible for cancer recurrance are different in their genetic makeup than those of the primary tumor”

When we consider the complexity of disease, especially cancer, along with the biological complexity of each individual patient, it’s nearly impossible to determine drug resistance with absolute certainty. But while predicting such reactions may be impossible, testing for them prior to actual treatment is not. By testing the patient’s cancer cells with various chemotherapy drug types we can observe the reactions and see a bit clearer into the patient’s future treatment. In fact, we can test combinations of drugs and pinpoint those showing the best response ex-vivo[2] using a tissue or blood sample from the patient. Using a method called “gene profiling” we look at micrometasteses which are cancerous cells shed in the blood after a primary tumor has been removed.

These particular cells are responsible for cancer recurring or a relapse and may differ in their genetic alterations from those of the primary tumor. [Georgia Institute of Technology (2013, August 12). Cancer cells appear to change while moving throughout body. ScienceDaily. Retrieved September 10, 2013, from http://www.sciencedaily.com­/releases/2013/08/130812154102.htm]. For this reason their chemo resistance may also be different from the actual tumor.

Chemosensitivity testing can help lower instances of cancer recurrence by guiding patients in choosing the most effective drug the first time around. Because it targets residual cells that are actually different in their genetic makeup than cells from the primary tumor, chemosensitivity testing is a more targeted approach to cancer treatment. By eliminating drugs that show resistance, chemosensitivity testing can help you make the best choices for your treatment. As with anything, absolute certainty is impossible, but the use of diagnostic testing and tools to complement chemo-therapy can greatly minimize instances of cancer recurrence.

[1] An adjuvant therapy is a term used to describe a secondary therapy used in conjunction with a primary therapy such as the removal of a tumor, which is sometimes followed by chemotherapy. In this case chemotherapy is used as a secondary, and precautionary therapy to kill any remaining cancer cells left behind after surgery and would be considered the adjuvant therapy, however it isn’t always an adjuvant therapy.

[2] Ex-vivo- A term used to describe a location outside of the organism where something takes place, usually testing or experimental in nature such as testing a sample of cancerous tissue taken from a patient.

Technical Information On Chemosensitivity Testing

A fundamental treatment option for cancer is chemotherapy. For each type of tumor, different chemotherapy regimes (drugs or drug combinations) exist. The efficacy of these regimes is usually determined by clinical trials and those regimes showing statistically to have the best success-rates are classified the most effective. However, an individual patient may respond differently to each therapy and it is a difficult task for the physician to choose the most appropriate from the available treatment regimes. Chemosensitivity testing can aid to select those drugs more likely to be effective than others for an individual patient.

Our chemosensitivity testing is based on genetic profiling of drug-metabolizing genes and cellular drug-target genes in the isolated tumor cells. The expression of these genes is determined by accurate technique of real-time quantitative PCR. From the academic literature it is known that the expression of drug metabolizing genes in tumor cells is influencing the action of the drug*1,2. Some drugs act directly on specific cellular molecules, so called drug targets. An effective response of such drugs requires the presence of these drug targets in the cells, which we can assess by measuring the gene expression of the drug target gene.

Several chemo-drugs (e.g. cyclophosphamide, capecitabine, irinotecan, dacarbazine) are virtually inactive in its parent form and need prior activation in the body, e.g. by liver enzymes. Such drugs are rather problematic to test ex-vivo on tumor-tissues with the widely used cell-viability chemosensitivity assays.

In contrast, chemosensitivity testing by our genetic profiling does not depend on prior activation of the test drugs by liver enzymes. The aim of adjuvant therapies is the elimination of residual cancer cells (micrometastases) which are responsible for relapse or metastasis after the primary tumor has been removed. Our philosophy is therefore to use isolated micrometastases for the resistance analyses, since these residual tumor cells should be actually killed by the therapy. It is well known from the literature that tumors are very heterogeneous. They do not consist of identical cancer cells, but are rather composed of groups of cells which may differ in regard of their genetic alterations. The cells shed in the blood stream forming micrometastases may consequently not be genetically identical with the average primary tumor, recently proven by academic work*3. Therefore, a targeted therapy against the disseminated cancer cells may be a more straightforward way to prevent the emergence of relapse and metastases.

Click here for a list of Testable Chemotherapeutic Drugs

Mechanisms of Drug Resistance and Susceptibility

Tumors may become resistant to multiple drugs by activation of functions like MDR or GST, leading to increased detoxification and efflux of chemotherapeutic drugs. We can measure the levels of these multidrug-resistance conferring functions in the tumor cells.

Some drugs need metabolic activation within the tumor cells by enzymatic functions. A reduced expression of these enzymes in the tumor cells may lead to diminished sensitivitiy to those drugs.

It has also been observed that a tumor might better respond to certain drugs, if the molecules which are inhibited by these drugs are increased (overexpressed) in the tumor cells. Such molecules are called drug-targets. The main drug-target for anthracycline drugs (e.g. doxorubicine) is topoisomerase II. Tumors with higher levels of topoisomerase II generally show better sensitivity to anthracyclines.

Her2 (ERBB2) is the drug-target for Herceptin, an antibody specifically directed against ERBB2. Besides breast cancer, Her2 can be detected in many different types of malignancies. Usually, effective treatment of breast cancer with Herceptin requires overexpression of Her2 in the tumor cells, which can be determined by genetic testing. Discordance of Her2 status between primary tumor and metastases can occur by acquiring Her2 activation during tumor progression. In breast cancer patients, circulating tumor cells have shown to overexpress Her2 despite Her2-negative primary tumor. Importantly, after such cases had been treated with Herceptin, clinical responses could have been achieved*4.

Especially in hematological malignancies, genetic malfunction induced by chromosomal rearrangements leads to the uncontrolled production of molecules which are targets for specifically designed anti-cancer agents. Leukemia positive for the bcr-abl chromosomal rearrangement can be efficiently treated with Gleevec. Whereas most cases of chronic myeloid leukemia (CML) are positive for bcr-abl and have a good prognosis, acute myeloid leukemia (AML) positive for bcr-abl is a rare disease, characterized by a poor prognosis, with resistance to induction chemotherapy and frequent relapses in responsive patients. Genetic testing for the presence of bcr-abl can identify those patients which profit from Gleevec treatment. As ever more specifically designed anticancer agents are developed and clinically used, the determination of the target molecules in the tumor cells gets more and more important to stratify patients for the appropriate use of expensive therapies. Examples of recently applied drugs are Avastin, Sutent or Bortezomib, all known to attack certain molecules frequently altered in many different tumors.

The treatment success of our clinical partners, who guide therapies according to our analytical findings convinces us that our methods are sensible. Evidence from the academic literature is supporting the principles of our strategy.* Beside the metabolic properties of the tumor cells, there are several other critical factors why the chemosensitivity tests cannot always predict that the tumor will respond as supposed by the results of our analyses:

The drug administered systemic must reach all the tumor cells

Patient-to-patient differences may exist how the drug is metabolized and excreted from the body

Subsets of disseminated tumor cells may be present which behave differently

Some cells may have yet unknown genetic mechanisms which render them resistant.

During therapy, tumor cells accumulate further mutations which may result in the selection of resistant clones.

Consequently, partial responses may occur and not necessarily a complete remission despite the results of in vitro testing has not indicated resistance. Since in vitro testing can not be absolutely accurate because of the mentioned reasons, our assay results should not be used as a reason to refuse giving chemotherapy. If a proven effective therapy has not yet been tried, the assay results should not determine that this therapy should not be used. However, the tests can help to choose drugs from the available therapy options that might be more effective than others . If resistance occurs to a drug, the tests can help to identify another agent that might work better.

What Types of Tumors Can Be Tested?

Most types of tumors can be tested, including tumors originating from lung, colon, breast, ovary, cervix, prostate, skin, intestine (stomach, gastric), esophagus, liver, kidney. In addition to these most prominent tumor diseases, other less frequent tumors can also be tested. Please inquire for special cases.

Hematological tumors can be assayed for typical rearrangements of hematological tumor cells to permit detection of minimal residual leukemia cells in the bloodstream and to monitor the success of treatment. If the therapy is effective, residual leukemia cells should disappear from the bloodstream.

Read More
We have established assays for the diagnosis of various chromosomal rearrangements occurring in leukemia. By identification of subtype associated translocations, prognosis or an appropriate therapy can be estimated. Additionally, detection of minimal residual lymphoma can be done by analysis of immune-receptor rearrangements.

Leukemia Genetic Testing

Typical chromosomal rearrangements like translocations are often associated with a certain type of hematological cancer. For example, the well known Philadelphia chromosome, which is the result of a translocation between the chromosomes 9 and 22 occurs in about 90% of CML cases.

Leukemia is categorized in subtypes which may differ regarding prognosis and the appropriate treatment modalities. Many subtypes are associated with distinct chromosomal abnormalities.

The sensitive detection of these rearrangements can be used to monitor minimal residual disease and consequently the success of an ongoing therapy.

We have established assays for the diagnosis of various chromosomal rearrangements occurring in leukemia. By identification of subtype associated translocations, prognosis or an appropriate therapy can be estimated.

Panel of translocation which can be determined at with testing:

Leukemia

Lymphoma Genetic Testing

Additionally, detection of minimal residual lymphoma can be done by analysis of immune-receptor rearrangements. The detection of individual, prominent VDJ-receptor rearrangements in the blood is conclusive for a clonal proliferation of lymphocytes, especially B-lymphocytes. VDJ-receptor rearrangements are found in 95 % of B-cell ALLs, but also in 14 % of T-cell ALLs.

Clonal expansion of T-cells can be diagnosed by detection of VJ-receptor rearrangements, which are found in 91 % of T-cell ALLs, but also in 55 % of B-cell ALLs.

Lymphoma

Read More
The concept of integrative medicine claims higher success rates if conventional anti-cancer therapy (e.g. chemotherapy) is combined with alternative medicine. Conventional therapy may be limited by toxicity to the patients or tumor resistance. Many agents from natural sources have shown to have anti-tumor activity. Moreover, some of these agents are able to modulate the cellular enzymatic functions causative for chemotherapy resistance in the tumor cells, which could render the chemoresistant tumor cells again sensitive to chemotherapy.

Drug-transporter molecules (e.g. MDR or MRP) may be induced in tumor cells by chemotherapy. As a consequence, increased efflux of drugs leads to multi-drug resistance of the tumor cells which is a serious problem in cancer treatment. Natural agents like Curcumin or Haelan 951 (an fermented soy-extract) are known modulators of MDR, possibly supporting chemotherapy of tumors showing the MDR-phenotype.

Another mechanism for multidrug resistance is induction of conjugating enzymes leading to increased detoxification of the chemo-drugs. In this context, elevated expression of GST/GCS in tumor cells play an important role. Ellagic acid, an inhibitor of GST may here used to modulate GST-related resistance.

Heat-shock proteins (HSP) may render tumor cells thermoresistant (see below “Hyperthermia”) and resistant to some chemo-drugs. Quercetin is an inhibitor of the heat-shock protein HSP27 and may be used for treatment if tumors show high levels of HSP27.

Testing the use of alternative medicine agents in conjunction with chemotherapy:

For many natural anti-cancer agents, mechanisms of action are known and genetic testing can provide useful advise for appropriate application. Beside the conventional drugs of chemotherapy, alternative agents are also useful in treatment of cancer. Those alternative medicine agents may have anti-cancer activity by directly killing tumor cells, e.g. by induction of apoptosis (programmed cell death). Alternative agents are reported to modulate cellular functions conferring chemo-resistance to the tumor cells. In such cases, supportive therapy with appropriate alternative agents may have synergistic action with conventional chemotherapy. Our testing determines which alternative agents are likely to be effective or which may have a beneficial use especially in conjunction with chemotherapy.

Read More
Beside chemotherapeutic or hormonal therapies that are directed against the malignant cells, certain alternative treatment options have the aim to stimulate the body’s immune cells and to augment the immune system in fighting the tumor. Numerous immuno-activating agents are available, e.g.

Botanicals (e.g. Mistletoe, Biobran, etc.
Thymus extracts: (e.g. Thymosin, Thymoject)
Cytokines (e.g. interleukin 2)
All these agents have a potent propensity to stimulate and activate Natural Killer (NK) cells. NK cells belong to the lymphocytes and play a very important role in the early defense of the immune system against viruses, bacteria and tumor cells. Activation of the NK cells is regulated by a subtle balance between positive and negative signals. Surface receptors on the NK cells transmit either activating or inhibiting signals into the cell.

In tumor patients, NK cells are often diminished in numbers and restricted in functionality. The extent of this impaired immune function correlates with disease progression and time of survival. Enhancement of the immune function is therefore a important therapeutic goal.

The mere number of NK cells is not sufficient to assess the functionality of this important defense system. An in vitro assay has been established in our lab to measure the capability of a patient’s immune cells to destroy tumor cells. For this, lymphocytes are isolated from a patients blood sample and incubated together with dye-labeled tumor-cells. Lysis of the tumor cells by the immune cells liberates the dye and can be quantified in the culture supernatant.

The amount of liberated dye reflects the actual, spontaneous NK cell activity (see Figure below). Beside the determination of the spontaneous NK cell activity, we can determine if the immune cells are susceptible to be stimulated by immuno-acitvation therapy. The percentage increase of tumor cell lysis compared to the spontaneous NK cell activity is a degree of capability of the NK cells to be activated. This allows the estimation of how promising a immune-stimulative therapy will be. During the course of such a therapy, treatment success could thereby be monitored with the assay.

Principle of Cellular NK Testing

NK Cell

Agents which can be tested in the Cellular NK-Test:

Basically, every substance claimed to activate the NK cells could be used in the assay. We routinely use thymus extracts, mistletoe extracts and interleukin 2. Other agents could be tested upon request. In such instances, please provide a sample of the agent to be tested.

Natural Killer Cells

Read More
Used as a way to diagnose, screen or monitor patients for certain types of cancers, tumor markers indicate elevated levels of a certain substance in blood, urine, or body tissue. The substance may vary according to the type of cancer and/or it’s progression. Below are some of those substances used as markers for the related cancer types. Note: Elevated levels of these substances is not a definitive of a cancer diagnosis, it only indicates the need for further testing.

AFP – Levels of alpha-Feto-Protein (AFP) are increased in Hepatoma and Teratoma (liver, pancreas, prostate). AFP has structural and functional similarities to albumin and is normally decreased in adults.
Aromatase is catalyzing the formation of C18 estrogens from C19 androgens. Inhibitory anti-cancer drugs of aromatase prevent the production of estrogens and consequently the growth of estrogen dependent tumors. Expression of aromatase in tumors is may be considered as a prerequisite for a rational therapy with aromatase inhibitors.
CA15-3 is a sensitive tumor marker for primary, preoperative and metastatic breast cancer. If you have breast cancer, it will be used in conjunction with other tests to evaluate the need for surgical intervention.
CA19-9 antigen has been shown to be elevated in the blood of some patients with gastrointestinal tumors. It is helpful during your post-therapeutic monitoring to determine the success of therapy, or can be used serially to ascertain the development of recurrence.
CA-125 is a highly useful marker for monitoring disease progression in ovarian cancers.
Click here to download a list of Tumor Markers and Genes that can be tested.

Read More

Still Have Questions?

Would you like to learn more about our treatment options? Send us a message and one of our friendly Patient Care Representatives will contact you shortly to answer any questions you may have. (** All Fields Required **)